Contrary to popular belief, we feel it is not good practice to routinely open your isolator doors to clean the interior. If running properly, the Isolator stays as clean (probably cleaner) as the last time you used it and runs virtually particle free. Opening the door is about the worst thing you can do. It Floods your equipment with Particulate Laden air. Open the door if you have a spill, or it needs mechanical scrubbing, then close it up and clean it again using our mop!