HDs must be stored separately from non-HDs (as currently required in <797>), with one possible exception. Those HDs on the NIOSH list that are not listed as antineoplastic agents, are available in final-manufactured dosage forms, and not manipulated other than counting for dispensing, may be co-mingled with non-HD stock if the entity’s policy allows. Unless the HDs are received in their final unit-dose or unit-of-use packaging, the storage of HDs must be stored in a room that is separate from non-HD storage. The restricted-access room must be under negative pressure, externally vented, and have at least 12 air changes per hour. Injectable HDs may be stored in the negative-pressure buffer room used for sterile preparations if there is sufficient room available and all particle-generating external packaging (such as coarse cardboard) has been removed prior to placement in the buffer room. If refrigerated antineoplastics are stocked, a refrigerator dedicated to storage of HDs is required in the HD storage area.