Negative Pressure Isolators
USP-800 CACI C-SCA AND C-PEC IN ONE UNIT
USP-800 C-SCA and C-PEC
Containment Segregated Compounding Area
Containment Primary Engineering Control
CACI Compounding Aseptic Containment Isolator - Negative Pressure Isolator
- Superior pharmacist and environmental protection vs. BSC
- Chemo Units/Custom – Combo unit shown
- Nuclear Pharmacy Units
- Automated picking chamber available
- Staging chamber can be added
- Containment Alarm System – Manual silence is required
- Unidirectional airflow in working and transfer chambers
- Virtually Particulate free Direct Compounding Area!!!!
- Guaranteed to meet or exceed USP 797, CETA, & NIOSH regulations.
XLTC 800
Comprehensive Aseptic Containment
The SAFEST
The MOST ASEPTIC
XLTC 800 has significant safety and aseptic benefits due to its isolated nature. Materials are brought into the uncontrolled negative pressure staging chamber and are opened from the protective environment of gloves and sleeves. Staging can be accommodated via integrated storage and refrigeration equipment. The middle chamber is the processing chamber for product wipe down and preparation into the far left chamber which is the direct compounding area.
Frequently Asked Questions
What safety features are incorporated into negative pressure isolators?
Negative pressure isolators incorporate safety features such as HEPA or ULPA filters for air filtration, airtight seals to prevent leaks, alarms for pressure changes, and secure glove ports to protect operators from exposure to hazardous substances.
How is airflow controlled and monitored in a negative pressure isolator?
Airflow in a negative pressure isolator is controlled and monitored using specialized HVAC systems that maintain a continuous flow of filtered air into the isolator. This creates a negative pressure environment that prevents contaminants from escaping. Pressure gauges and alarms are used to monitor and ensure consistent airflow.
What materials are typically used to construct negative pressure isolators?
Negative pressure isolators are typically constructed from materials such as stainless steel for durability and chemical resistance, glass or polycarbonate for visibility, and specialized seals and gaskets to ensure airtight conditions.
How do negative pressure isolators help in contamination control?
Negative pressure isolators help in contamination control by maintaining a lower pressure inside the isolator compared to the external environment. This ensures that any contaminants are contained within the isolator, preventing their release into the surrounding area and protecting both the product and personnel.
What are the maintenance and testing requirements for negative pressure isolators?
Maintenance and testing requirements for negative pressure isolators include regular inspection and replacement of filters, calibration of pressure gauges, leak testing to ensure airtight conditions, and routine cleaning and decontamination. Performance tests, such as airflow and particle count tests, should be conducted periodically to ensure optimal operation.
How are negative pressure isolators validated for their intended use?
Negative pressure isolators are validated through a series of tests and qualifications, including installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ). These tests verify that the isolator meets design specifications, operates correctly under all intended conditions, and consistently performs to the required standards.
What are the common challenges associated with using negative pressure isolators?
Common challenges with using negative pressure isolators include maintaining airtight seals, ensuring consistent airflow and pressure levels, managing filter replacements, and conducting thorough cleaning and decontamination. Proper training and regular maintenance are essential to address these challenges effectively.
Can negative pressure isolators be used for handling hazardous materials?
Yes, negative pressure isolators are designed for handling hazardous materials. They provide a controlled environment that prevents the release of harmful substances, protecting both personnel and the surrounding environment from contamination.
