Archives for January 2014

Adopting appropriate aseptic technique

By Fran McAteer, Microbiology Research Associates

Compounding sterile preparations (CSPs) are made utilizing aseptic technique. Aseptic technique is a microbiological term referring to the prevention of microorganism contamination. The procedure involves the use of specialized equipment, sterile apparel, meticulous processing, and continuous cleaning.

Aseptic necrosis facts

  • Aseptic necrosis is a bone condition that results from poor blood supply to an area of bone, causing localized bone death.
  • Aseptic necrosis can be caused by trauma, damage to the blood vessels that supply bone its oxygen, poor blood circulation to the bone, abnormally thick blood (hypercoagulable state), and atherosclerosis or inflammation of the blood vessel walls (vasculitis).

Aseptic simulation test challenged with microorganisms for validation of pharmacy operators.

 Aseptic technique of pharmacy operators was assessed using simulated media-fill tests challenged with microorganisms. Simulation of the process was done in accordance with multiple transfer steps using tryptone soya broth. All stoppers of broth medium vials were deliberately contaminated with a challenge micro-organism (Enterococcus faecalis). Each final preparation

EVALUATION OF ASEPTIC TECHNIQUES AND CHLORHEXIDINE ON THE RATE OF CATHETER-ASSOCIATED URINARY-TRACT INFECTION

Aseptic techniques used together with chlorhexidine reduced the infection rate and prevented cross-infection in patients undergoing urinary-tract catheterisation. Infection of the bladder appears to have arisen by contamination of the catheter-meatal junction, at which site antiseptic prophylaxis in the presence of bathing was ineffective. Patients having short-term catheterisation should not be placed in baths, since wetting the perineum will contaminate the urethral meatus with mixed enterobacteria, predisposing the female patient in particular to infection.