Archives for December 2013

Aseptic services

Located within the pharmacy department is the Aseptic Services Suite. The suite is comprised of many sterile rooms that allow for the preparation and production of high risk medicines for the hospital.


Adopting appropriate aseptic technique

Compounding sterile preparations (CSPs) are made utilizing aseptic technique. Aseptic technique is a microbiological term referring to the prevention of microorganism contamination. The procedure involves the use of specialized equipment, sterile apparel, meticulous processing, and continuous cleaning.

Evaluating aseptic technique of pharmacy personnel.

A procedure for validating the effectiveness of a training program in aseptic technique for admixture personnel and for monitoring the aseptic technique of those trained is described. Double-strength soybean casein digest broth was prepared as the culture media. Technicians were instructed to prepare 50 sample i.v. admixtures after the structured one-week orientation and training period. The sample admixtures were cultured for sterility by a total-culturing method. An ongoing random-sampling plan was implemented to monitor the technique of the trained technicians. Six technicians completed the orientation program, and five compounded the validation admixtures aseptically. The ongoing monitoring revealed that the technicians who were validated have continued to perform at acceptable levels. This program validated that the personnel had adequate training in aseptic technique and the necessary skills for performing the aseptic manipulations required in i.v. admixture compounding.

How to Earn Pharmacy Compounding Accreditation

Drug compounding made the wrong kind of headlines in October 2012 when U.S. health officials announced that patients injected with products prepared by the New England Compounding Center were contracting and dying fromĀ fungal meningitis. The toll contaminated compounded medications will take in lives, dollars and the professional reputation of pharmacy practitioners may not be known for years.

Safe aseptic preparation in the pharmacy and on the ward

Injectable medicines are prepared prior to use on the wards and in the pharmacy. In this article, we describe how to organise this process. A risk based approach is suggested to direct the aseptic preparation policy in a hospital. Examples from the Czech Republic and The Netherlands are used.